PDB Information

PDB3QKK
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and SAR of spirochromane Akt inhibitors.
Kallan, N.C., Spencer, K.L., Blake, J.F., Xu, R., Heizer, J., Bencsik, J.R., Mitchell, I.S., Gloor, S.L., Martinson, M., Risom, T., Gross, S.D., Morales, T.H., Wu, W.I., Vigers, G.P., Brandhuber, B.J., Skelton, N.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-02-01
Resolution2.300
CATH Insert Date03 Apr, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 04 Apr, 2011 Chopped
C 04 Apr, 2011 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3qkkA01 30 Aug, 2013 3.30.200.20 Assigned
3qkkA02 30 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P31749 AKT1_HUMAN Homo sapiens RAC-alpha serine/threonine-protein kinase
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta