PDB Information

PDB3QK0
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors.
D'Angelo, N.D., Kim, T.S., Andrews, K., Booker, S.K., Caenepeel, S., Chen, K., D'Amico, D., Freeman, D., Jiang, J., Liu, L., McCarter, J.D., San Miguel, T., Mullady, E.L., Schrag, M., Subramanian, R., Tang, J., Wahl, R.C., Wang, L., Whittington, D.A., Wu, T., Xi, N., Xu, Y., Yakowec, P., Yang, K., Zalameda, L.P., Zhang, N., Hughes, P., Norman, M.H.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-01-31
Resolution2.850
CATH Insert Date03 Apr, 2011

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 04 Apr, 2011 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3qk0A01 04 Sep, 2013 3.10.20.90 Assigned
3qk0A02 04 Sep, 2013 2.60.40.150 Assigned
3qk0A03 04 Sep, 2013 1.25.40.70 Assigned
3qk0A04 04 Sep, 2013 3.30.1010.10 Assigned
3qk0A05 04 Sep, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform