PDB 3qjz

PDB Information

PDB3QJZ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors.
D'Angelo, N.D., Kim, T.S., Andrews, K., Booker, S.K., Caenepeel, S., Chen, K., D'Amico, D., Freeman, D., Jiang, J., Liu, L., McCarter, J.D., San Miguel, T., Mullady, E.L., Schrag, M., Subramanian, R., Tang, J., Wahl, R.C., Wang, L., Whittington, D.A., Wu, T., Xi, N., Xu, Y., Yakowec, P., Yang, K., Zalameda, L.P., Zhang, N., Hughes, P., Norman, M.H.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-01-31
Resolution2.900
CATH Insert Date03 Apr, 2011

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 04 Apr, 2011 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3qjzA01 04 Sep, 2013 3.10.20.90 Assigned
3qjzA02 04 Sep, 2013 2.60.40.150 Assigned
3qjzA03 04 Sep, 2013 1.25.40.70 Assigned
3qjzA04 04 Sep, 2013 3.30.1010.10 Assigned
3qjzA05 04 Sep, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform