PDB 3qbh

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PDB Links
Overview

PDB Information

PDB	3QBH
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Rueeger, H., Rondeau, J.M., McCarthy, C., Mobitz, H., Tintelnot-Blomley, M., Neumann, U., Desrayaud, S. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2011-01-13
Resolution	2.240
CATH Insert Date	27 Mar, 2011

PDB Images (10)

Image of CATH 3qbh

3qbh

PDB 3qbh

Image of CATH 3qbhA

3qbhA

PDB Chain 3qbhA

Image of CATH 3qbhB

3qbhB

PDB Chain 3qbhB

Image of CATH 3qbhC

3qbhC

PDB Chain 3qbhC

Image of CATH 3qbhA01

3qbhA01

CATH Domain 3qbhA01

Image of CATH 3qbhA02

3qbhA02

CATH Domain 3qbhA02

Image of CATH 3qbhB01

3qbhB01

CATH Domain 3qbhB01

Image of CATH 3qbhB02

3qbhB02

CATH Domain 3qbhB02

Image of CATH 3qbhC01

3qbhC01

CATH Domain 3qbhC01

Image of CATH 3qbhC02

3qbhC02

CATH Domain 3qbhC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	28 Mar, 2011	Chopped
B	28 Mar, 2011	Chopped
C	28 Mar, 2011	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3qbhA01	01 Apr, 2011	2.40.70.10	Assigned
3qbhA02	01 Apr, 2011	2.40.70.10	Assigned
3qbhB01	01 Apr, 2011	2.40.70.10	Assigned
3qbhB02	01 Apr, 2011	2.40.70.10	Assigned
3qbhC01	01 Apr, 2011	2.40.70.10	Assigned
3qbhC02	01 Apr, 2011	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1