PDB 3q32

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Overview

PDB Information

PDB	3Q32
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Pyrrolo[1,2-f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3. Harikrishnan, L.S., Kamau, M.G., Wan, H., Inghrim, J.A., Zimmermann, K., Sang, X., Mastalerz, H.A., Johnson, W.L., Zhang, G., Lombardo, L.J., Poss, M.A., Trainor, G.L., Tokarski, J.S., Lorenzi, M.V., You, D., Gottardis, M.M., Baldwin, K.F., Lippy, J., Nirschl, D.S., Qiu, R., Miller, A.V., Khan, J., Sack, J.S., Purandare, A.V. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2010-12-21
Resolution	2.500
CATH Insert Date	20 Feb, 2011

PDB Images (7)

Image of CATH 3q32

3q32

PDB 3q32

Image of CATH 3q32A

3q32A

PDB Chain 3q32A

Image of CATH 3q32B

3q32B

PDB Chain 3q32B

Image of CATH 3q32A01

3q32A01

CATH Domain 3q32A01

Image of CATH 3q32A02

3q32A02

CATH Domain 3q32A02

Image of CATH 3q32B01

3q32B01

CATH Domain 3q32B01

Image of CATH 3q32B02

3q32B02

CATH Domain 3q32B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	21 Feb, 2011	Chopped
B	21 Feb, 2011	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3q32A01	24 Feb, 2011	3.30.200.20	Assigned
3q32A02	24 Feb, 2011	1.10.510.10	Assigned
3q32B01	24 Feb, 2011	3.30.200.20	Assigned
3q32B02	24 Feb, 2011	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2