PDB Information

PDB3Q2H
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHomo sapiens
Primary Citation
The design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis
De Savi, C., Pape, A., Cumming, J.G., Ting, A., Smith, P.D., Burrows, J.N., Mills, M., Davies, C., Lamont, S., Milne, D., Cook, C., Moore, P., Sawyer, Y., Gerhardt, S.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2010-12-20
Resolution2.330
CATH Insert Date03 Apr, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 04 Apr, 2011 Chopped
B 04 Apr, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3q2hA01 24 Jan, 2013 3.40.390.10 Assigned
3q2hA02 24 Jan, 2013 3.40.1620.60 Assigned
3q2hB01 24 Jan, 2013 3.40.390.10 Assigned
3q2hB02 24 Jan, 2013 3.40.1620.60 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9UHI8 ATS1_HUMAN Homo sapiens A disintegrin and metalloproteinase with thrombospondin motifs 1
Q9UHI8 ATS1_HUMAN Homo sapiens A disintegrin and metalloproteinase with thrombospondin motifs 1