PDB Information

PDB3PSB
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
The Discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors.
Buckmelter, A.J., Ren, L., Laird, E.R., Rast, B., Miknis, G., Wenglowsky, S., Schlachter, S., Welch, M., Tarlton, E., Grina, J., Lyssikatos, J., Brandhuber, B.J., Morales, T., Randolph, N., Vigers, G., Martinson, M., Callejo, M.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-12-01
Resolution3.400
CATH Insert Date23 Jan, 2011

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
B 24 Jan, 2011 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3psbA01 20 Feb, 2011 3.30.200.20 Assigned
3psbA02 20 Feb, 2011 1.10.510.10 Assigned
3psbB01 20 Feb, 2011 3.30.200.20 Assigned
3psbB02 20 Feb, 2011 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf