PDB Information

PDB3PRE
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.
Liu, K.K., Huang, X., Bagrodia, S., Chen, J.H., Greasley, S., Cheng, H., Sun, S., Knighton, D., Rodgers, C., Rafidi, K., Zou, A., Xiao, J., Yan, S.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-11-29
Resolution2.910
CATH Insert Date13 Feb, 2011

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Feb, 2011 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3preA01 19 Feb, 2011 3.10.20.90 Assigned
3preA02 19 Feb, 2011 2.60.40.150 Assigned
3preA03 19 Feb, 2011 1.25.40.70 Assigned
3preA04 19 Feb, 2011 3.30.1010.10 Assigned
3preA05 19 Feb, 2011 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform