PDB Information

Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer.
Dong, Q., Dougan, D.R., Gong, X., Halkowycz, P., Jin, B., Kanouni, T., O'Connell, S.M., Scorah, N., Shi, L., Wallace, M.B., Zhou, F.
HeaderTransferase/Transferase Inhibitor
CATH Insert Date27 Feb, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Feb, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3pp1A01 25 Sep, 2013 Assigned
3pp1A02 25 Sep, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1