PDB 3pp1

PDB Information

PDB3PP1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer.
Dong, Q., Dougan, D.R., Gong, X., Halkowycz, P., Jin, B., Kanouni, T., O'Connell, S.M., Scorah, N., Shi, L., Wallace, M.B., Zhou, F.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-11-23
Resolution2.700
CATH Insert Date27 Feb, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Feb, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3pp1A01 25 Sep, 2013 3.30.200.20 Assigned
3pp1A02 25 Sep, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1