PDB Information

PDB3P79
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD).
Moffett, K., Konteatis, Z., Nguyen, D., Shetty, R., Ludington, J., Fujimoto, T., Lee, K.J., Chai, X., Namboodiri, H., Karpusas, M., Dorsey, B., Guarnieri, F., Bukhtiyarova, M., Springman, E., Michelotti, E.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-10-12
Resolution2.100
CATH Insert Date16 Oct, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3p79A01 24 Jan, 2013 3.30.200.20 Assigned
3p79A02 24 Jan, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P47811 MK14_MOUSE Mus musculus Mitogen-activated protein kinase 14