PDB Information

PDB3P78
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD).
Moffett, K., Konteatis, Z., Nguyen, D., Shetty, R., Ludington, J., Fujimoto, T., Lee, K.J., Chai, X., Namboodiri, H., Karpusas, M., Dorsey, B., Guarnieri, F., Bukhtiyarova, M., Springman, E., Michelotti, E.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-10-12
Resolution2.3
CATH Insert Date16 Oct, 2011

PDB Images (4)

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3p78A01 24 Jan, 2013 3.30.200.20 Assigned
3p78A02 24 Jan, 2013 1.10.510.10 Assigned

Uniprot Entries (1)

Accession Gene ID Taxon Description
P47811 MK14_MOUSE Mus musculus CRK1