PDB Information

PDB3P08
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A novel, specific BTK inhibitor antagonizes BCR and FcgR signaling and suppresses inflammatory arthritis
Di Paolo, J., Huang, T., Balazs, M., Barbosa, J., Barck, K.H., Bravo, B., Carano, R.A.D., Darrow, J., Davies, D.R., DeForge, L.E., Diehl, L., Ferrando, R., Gallion, S.L., Gianetti, A.M., Gribling, P., Hurez, V., Hymowitz, S.G., Jones, R., Kropf, J.E., Lee, W.P., Maciejewski, P.M., Mitchell, S.A., Rong, H., Staker, B.L., Whitney, J.A., Yeh, S., Young, W., Yu, C., Zhang, J., Reif, K., Currie, K.S.
To be Published
HeaderTransferase
Released2010-09-27
Resolution2.300
CATH Insert Date07 Nov, 2010

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2010 Chopped
B 07 Nov, 2010 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3p08A01 17 Feb, 2011 3.30.200.20 Assigned
3p08A02 17 Feb, 2011 1.10.510.10 Assigned
3p08B01 17 Feb, 2011 3.30.200.20 Assigned
3p08B02 17 Feb, 2011 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK