PDB 3oy1

PDB Information

PDB3OY1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhibitors with in vitro CNS-like pharmacokinetic properties prevent neurodegeneration.
Probst, G.D., Bowers, S., Sealy, J.M., Truong, A.P., Hom, R.K., Galemmo, R.A., Konradi, A.W., Sham, H.L., Quincy, D.A., Pan, H., Yao, N., Lin, M., Toth, G., Artis, D.R., Zmolek, W., Wong, K., Qin, A., Lorentzen, C., Nakamura, D.F., Quinn, K.P., Sauer, J.M., Powell, K., Ruslim, L., Wright, S., Chereau, D., Ren, Z., Anderson, J.P., Bard, F., Yednock, T.A., Griswold-Prenner, I.
Bioorg.Med.Chem.Lett.
HeaderTransherase/Transferase Inhibitor
Released2010-09-22
Resolution1.700
CATH Insert Date21 Aug, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 22 Aug, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3oy1A01 25 Aug, 2011 3.30.200.20 Assigned
3oy1A02 25 Aug, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P53779 MK10_HUMAN Homo sapiens Mitogen-activated protein kinase 10