PDB 3ow4

PDB Links
Overview

PDB Information

PDB	3OW4
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors. Bencsik, J.R., Xiao, D., Blake, J.F., Kallan, N.C., Mitchell, I.S., Spencer, K.L., Xu, R., Gloor, S.L., Martinson, M., Risom, T., Woessner, R.D., Dizon, F., Wu, W.I., Vigers, G.P., Brandhuber, B.J., Skelton, N.J., Prior, W.W., Murray, L.J. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2010-09-17
Resolution	2.600
CATH Insert Date	23 Jan, 2011

PDB Images (9)

Image of CATH 3ow4

3ow4

PDB 3ow4

Image of CATH 3ow4A

3ow4A

PDB Chain 3ow4A

Image of CATH 3ow4B

3ow4B

PDB Chain 3ow4B

Image of CATH 3ow4C

3ow4C

PDB Chain 3ow4C

Image of CATH 3ow4D

3ow4D

PDB Chain 3ow4D

Image of CATH 3ow4A01

3ow4A01

CATH Domain 3ow4A01

Image of CATH 3ow4A02

3ow4A02

CATH Domain 3ow4A02

Image of CATH 3ow4B01

3ow4B01

CATH Domain 3ow4B01

Image of CATH 3ow4B02

3ow4B02

CATH Domain 3ow4B02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	24 Jan, 2011	Chopped
B	24 Jan, 2011	Chopped
C	24 Jan, 2011	Rejected
D	24 Jan, 2011	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3ow4A01	30 Aug, 2013	3.30.200.20	Assigned
3ow4A02	30 Aug, 2013	1.10.510.10	Assigned
3ow4B01	30 Aug, 2013	3.30.200.20	Assigned
3ow4B02	30 Aug, 2013	1.10.510.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P49841	GSK3B_HUMAN	Homo sapiens	Glycogen synthase kinase-3 beta
P31749	AKT1_HUMAN	Homo sapiens	RAC-alpha serine/threonine-protein kinase
P31749	AKT1_HUMAN	Homo sapiens	RAC-alpha serine/threonine-protein kinase