PDB Information

PDB3OVX
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors.
Cai, J., Robinson, J., Belshaw, S., Everett, K., Fradera, X., van Zeeland, M., van Berkom, L., van Rijnsbergen, P., Popplestone, L., Baugh, M., Dempster, M., Bruin, J., Hamilton, W., Kinghorn, E., Westwood, P., Kerr, J., Rankovic, Z., Arbuckle, W., Bennett, D.J., Jones, P.S., Long, C., Martin, I., Uitdehaag, J.C., Meulemans, T.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2010-09-17
Resolution1.490
CATH Insert Date23 Jan, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
B 24 Jan, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3ovxA00 17 Feb, 2011 3.90.70.10 Assigned
3ovxB00 17 Feb, 2011 3.90.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P25774 CATS_HUMAN Homo sapiens Cathepsin S
P25774 CATS_HUMAN Homo sapiens Cathepsin S