PDB Information

PDB3OMV
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
Hatzivassiliou, G., Song, K., Yen, I., Brandhuber, B.J., Anderson, D.J., Alvarado, R., Ludlam, M.J., Stokoe, D., Gloor, S.L., Vigers, G., Morales, T., Aliagas, I., Liu, B., Sideris, S., Hoeflich, K.P., Jaiswal, B.S., Seshagiri, S., Koeppen, H., Belvin, M., Friedman, L.S., Malek, S.
Nature
HeaderTransferase
Released2010-08-27
Resolution4.000
CATH Insert Date19 Sep, 2010

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 20 Sep, 2010 Chopped
B 20 Sep, 2010 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3omvA01 17 Feb, 2011 3.30.200.20 Assigned
3omvA02 17 Feb, 2011 1.10.510.10 Assigned
3omvB01 17 Feb, 2011 3.30.200.20 Assigned
3omvB02 17 Feb, 2011 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04049 RAF1_HUMAN Homo sapiens RAF proto-oncogene serine/threonine-protein kinase
P04049 RAF1_HUMAN Homo sapiens RAF proto-oncogene serine/threonine-protein kinase