PDB 3oeu

PDB Links
Overview

PDB Information

PDB	3OEU
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Blackburn, C., Barrett, C., Blank, J.L., Bruzzese, F.J., Bump, N., Dick, L.R., Fleming, P., Garcia, K., Hales, P., Hu, Z., Jones, M., Liu, J.X., Sappal, D.S., Sintchak, M.D., Tsu, C., Gigstad, K.M. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2010-08-13
Resolution	2.600
CATH Insert Date	24 Jul, 2011

PDB Images (57)

3oeu

PDB 3oeu

3oeu1

PDB Chain 3oeu1

3oeu2

PDB Chain 3oeu2

3oeuA

PDB Chain 3oeuA

3oeuB

PDB Chain 3oeuB

3oeuC

PDB Chain 3oeuC

3oeuD

PDB Chain 3oeuD

3oeuE

PDB Chain 3oeuE

3oeuF

PDB Chain 3oeuF

3oeuG

PDB Chain 3oeuG

3oeuH

PDB Chain 3oeuH

3oeuI

PDB Chain 3oeuI

3oeuJ

PDB Chain 3oeuJ

3oeuK

PDB Chain 3oeuK

3oeuL

PDB Chain 3oeuL

3oeuM

PDB Chain 3oeuM

3oeuN

PDB Chain 3oeuN

3oeuO

PDB Chain 3oeuO

3oeuP

PDB Chain 3oeuP

3oeuQ

PDB Chain 3oeuQ

3oeuR

PDB Chain 3oeuR

3oeuS

PDB Chain 3oeuS

3oeuT

PDB Chain 3oeuT

3oeuU

PDB Chain 3oeuU

3oeuV

PDB Chain 3oeuV

3oeuW

PDB Chain 3oeuW

3oeuX

PDB Chain 3oeuX

3oeuY

PDB Chain 3oeuY

3oeuZ

PDB Chain 3oeuZ

3oeu100

CATH Domain 3oeu100

3oeu200

CATH Domain 3oeu200

3oeuA00

CATH Domain 3oeuA00

3oeuB00

CATH Domain 3oeuB00

3oeuC00

CATH Domain 3oeuC00

3oeuD00

CATH Domain 3oeuD00

3oeuE00

CATH Domain 3oeuE00

3oeuF00

CATH Domain 3oeuF00

3oeuG00

CATH Domain 3oeuG00

3oeuH00

CATH Domain 3oeuH00

3oeuI00

CATH Domain 3oeuI00

3oeuJ00

CATH Domain 3oeuJ00

3oeuK00

CATH Domain 3oeuK00

3oeuL00

CATH Domain 3oeuL00

3oeuM00

CATH Domain 3oeuM00

3oeuN00

CATH Domain 3oeuN00

3oeuO00

CATH Domain 3oeuO00

3oeuP00

CATH Domain 3oeuP00

3oeuQ00

CATH Domain 3oeuQ00

3oeuR00

CATH Domain 3oeuR00

3oeuS00

CATH Domain 3oeuS00

3oeuT00

CATH Domain 3oeuT00

3oeuU00

CATH Domain 3oeuU00

3oeuV00

CATH Domain 3oeuV00

3oeuW00

CATH Domain 3oeuW00

3oeuX00

CATH Domain 3oeuX00

3oeuY00

CATH Domain 3oeuY00

3oeuZ00

CATH Domain 3oeuZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
1	01 Aug, 2011	Chopped
2	01 Aug, 2011	Chopped
A	01 Aug, 2011	Chopped
B	01 Aug, 2011	Chopped
C	01 Aug, 2011	Chopped
D	01 Aug, 2011	Chopped
E	01 Aug, 2011	Chopped
F	01 Aug, 2011	Chopped
G	01 Aug, 2011	Chopped
H	01 Aug, 2011	Chopped
I	01 Aug, 2011	Chopped
J	01 Aug, 2011	Chopped
K	01 Aug, 2011	Chopped
L	01 Aug, 2011	Chopped
M	01 Aug, 2011	Chopped
N	01 Aug, 2011	Chopped
O	01 Aug, 2011	Chopped
P	01 Aug, 2011	Chopped
Q	01 Aug, 2011	Chopped
R	01 Aug, 2011	Chopped
S	01 Aug, 2011	Chopped
T	01 Aug, 2011	Chopped
U	01 Aug, 2011	Chopped
V	01 Aug, 2011	Chopped
W	01 Aug, 2011	Chopped
X	01 Aug, 2011	Chopped
Y	01 Aug, 2011	Chopped
Z	01 Aug, 2011	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3oeu100	12 Aug, 2011	3.60.20.10	Assigned
3oeu200	12 Aug, 2011	3.60.20.10	Assigned
3oeuA00	04 Feb, 2013	3.60.20.10	Assigned
3oeuB00	04 Feb, 2013	3.60.20.10	Assigned
3oeuC00	04 Feb, 2013	3.60.20.10	Assigned
3oeuD00	08 Feb, 2013	3.60.20.10	Assigned
3oeuE00	12 Aug, 2011	3.60.20.10	Assigned
3oeuF00	12 Aug, 2011	3.60.20.10	Assigned
3oeuG00	12 Aug, 2011	3.60.20.10	Assigned
3oeuH00	12 Aug, 2011	3.60.20.10	Assigned
3oeuI00	12 Aug, 2011	3.60.20.10	Assigned
3oeuJ00	12 Aug, 2011	3.60.20.10	Assigned
3oeuK00	12 Aug, 2011	3.60.20.10	Assigned
3oeuL00	12 Aug, 2011	3.60.20.10	Assigned
3oeuM00	12 Aug, 2011	3.60.20.10	Assigned
3oeuN00	12 Aug, 2011	3.60.20.10	Assigned
3oeuO00	04 Feb, 2013	3.60.20.10	Assigned
3oeuP00	04 Feb, 2013	3.60.20.10	Assigned
3oeuQ00	04 Feb, 2013	3.60.20.10	Assigned
3oeuR00	08 Feb, 2013	3.60.20.10	Assigned
3oeuS00	12 Aug, 2011	3.60.20.10	Assigned
3oeuT00	12 Aug, 2011	3.60.20.10	Assigned
3oeuU00	12 Aug, 2011	3.60.20.10	Assigned
3oeuV00	12 Aug, 2011	3.60.20.10	Assigned
3oeuW00	12 Aug, 2011	3.60.20.10	Assigned
3oeuX00	12 Aug, 2011	3.60.20.10	Assigned
3oeuY00	12 Aug, 2011	3.60.20.10	Assigned
3oeuZ00	12 Aug, 2011	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1