PDB 3o95

PDB Information

PDB3O95
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a 3-Pyridylacetic Acid Derivative (TAK-100) as a Potent, Selective and Orally Active Dipeptidyl Peptidase IV (DPP-4) Inhibitor.
Miyamoto, Y., Banno, Y., Yamashita, T., Fujimoto, T., Oi, S., Moritoh, Y., Asakawa, T., Kataoka, O., Yashiro, H., Takeuchi, K., Suzuki, N., Ikedo, K., Kosaka, T., Tsubotani, S., Tani, A., Sasaki, M., Funami, M., Amano, M., Yamamoto, Y., Aertgeerts, K., Yano, J., Maezaki, H.
J.Med.Chem.
HeaderHydrolase,Signaling Protein/Inhibitor
Released2010-08-03
Resolution2.850
CATH Insert Date30 Jan, 2011

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 31 Jan, 2011 Chopped
B 31 Jan, 2011 Chopped
C 31 Jan, 2011 Chopped
D 31 Jan, 2011 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3o95A01 18 Feb, 2011 2.140.10.30 Assigned
3o95A02 18 Feb, 2011 3.40.50.1820 Assigned
3o95B01 18 Feb, 2011 2.140.10.30 Assigned
3o95B02 18 Feb, 2011 3.40.50.1820 Assigned
3o95C01 18 Feb, 2011 2.140.10.30 Assigned
3o95C02 18 Feb, 2011 3.40.50.1820 Assigned
3o95D01 18 Feb, 2011 2.140.10.30 Assigned
3o95D02 18 Feb, 2011 3.40.50.1820 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
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