PDB 3o8a

PDB Information

PDB3O8A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model.
Booker, M.L., Bastos, C.M., Kramer, M.L., Barker, R.H., Skerlj, R., Sidhu, A.B., Deng, X., Celatka, C., Cortese, J.F., Guerrero Bravo, J.E., Crespo Llado, K.N., Serrano, A.E., Angulo-Barturen, I., Jimenez-Diaz, M.B., Viera, S., Garuti, H., Wittlin, S., Papastogiannidis, P., Lin, J.W., Janse, C.J., Khan, S.M., Duraisingh, M., Coleman, B., Goldsmith, E.J., Phillips, M.A., Munoz, B., Wirth, D.F., Klinger, J.D., Wiegand, R., Sybertz, E.
J.Biol.Chem.
HeaderOxidoreductase
Released2010-08-02
Resolution2.300
CATH Insert Date22 Aug, 2010

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 23 Aug, 2010 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3o8aA00 16 Feb, 2011 3.20.20.70 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q08210 PYRD_PLAF7 Plasmodium falciparum 3D7 Dihydroorotate dehydrogenase (quinone), mitochondrial