×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB 3o50

PDB Information

PDB3O50
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.
Cee, V.J., Schenkel, L.B., Hodous, B.L., Deak, H.L., Nguyen, H.N., Olivieri, P.R., Romero, K., Bak, A., Be, X., Bellon, S., Bush, T.L., Cheng, A.C., Chung, G., Coats, S., Eden, P.M., Hanestad, K., Gallant, P.L., Gu, Y., Huang, X., Kendall, R.L., Lin, M.H., Morrison, M.J., Patel, V.F., Radinsky, R., Rose, P.E., Ross, S., Sun, J.R., Tang, J., Zhao, H., Payton, M., Geuns-Meyer, S.D.
J.Med.Chem.
HeaderTransferase
Released2010-07-27
Resolution2.000
CATH Insert Date22 Aug, 2010

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 23 Aug, 2010 Chopped
B 23 Aug, 2010 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3o50A01 17 Feb, 2011 3.30.200.20 Assigned
3o50A02 17 Feb, 2011 1.10.510.10 Assigned
3o50B01 17 Feb, 2011 3.30.200.20 Assigned
3o50B02 17 Feb, 2011 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
CATH-Gene3D is a Global Biodata Core Resource Learn more...