PDB Information

PDB3NTZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.
Zhang, X., Zhou, X., Kisliuk, R.L., Piraino, J., Cody, V., Gangjee, A.
Bioorg.Med.Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2010-07-06
Resolution1.350
CATH Insert Date29 May, 2011

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2011 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3ntzA00 01 Jun, 2011 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase