Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region.
Probst, G.D., Bowers, S., Sealy, J.M., Stupi, B., Dressen, D., Jagodzinska, B.M., Aquino, J., Gailunas, A., Truong, A.P., Tso, L., Xu, Y.Z., Hom, R.K., John, V., Tung, J.S., Pleiss, M.A., Tucker, J.A., Konradi, A.W., Sham, H.L., Jagodzinski, J., Toth, G., Brecht, E., Yao, N., Pan, H., Lin, M., Artis, D.R., Ruslim, L., Bova, M.P., Sinha, S., Yednock, T.A., Gauby, S., Zmolek, W., Quinn, K.P., Sauer, J.M.
Bioorg.Med.Chem.Lett.