PDB 3ns7

PDB Information

PDB3NS7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Succinic acid amides as P2-P3 replacements for inhibitors of interleukin-1beta converting enzyme (ICE or caspase 1).
Galatsis, P., Caprathe, B., Gilmore, J., Thomas, A., Linn, K., Sheehan, S., Harter, W., Kostlan, C., Lunney, E., Stankovic, C., Rubin, J., Brady, K., Allen, H., Talanian, R.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2010-07-01
Resolution2.600
CATH Insert Date21 Aug, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 Aug, 2011 Chopped
B 22 Aug, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3ns7A00 25 Aug, 2011 3.40.50.1460 Assigned
3ns7B00 25 Aug, 2011 3.30.70.1470 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29466 CASP1_HUMAN Homo sapiens Caspase-1
P29466 CASP1_HUMAN Homo sapiens Caspase-1