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PDB 3ncz

PDB Information

PDB3NCZ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 2, optimization for blood pressure reduction in spontaneously hypertensive rats.
Ginn, J.D., Bosanac, T., Chen, R., Cywin, C., Hickey, E., Kashem, M., Kerr, S., Kugler, S., Li, X., Prokopowicz, A., Schlyer, S., Smith, J.D., Turner, M.R., Wu, F., Young, E.R.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-06-06
Resolution3.000
CATH Insert Date23 Jan, 2011

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
B 24 Jan, 2011 Chopped
C 24 Jan, 2011 Chopped
D 24 Jan, 2011 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3nczA01 17 Feb, 2011 3.30.200.20 Assigned
3nczA02 17 Feb, 2011 1.10.510.10 Assigned
3nczB01 17 Feb, 2011 3.30.200.20 Assigned
3nczB02 17 Feb, 2011 1.10.510.10 Assigned
3nczC01 17 Feb, 2011 3.30.200.20 Assigned
3nczC02 17 Feb, 2011 1.10.510.10 Assigned
3nczD01 17 Feb, 2011 3.30.200.20 Assigned
3nczD02 17 Feb, 2011 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
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