PDB Information

PDB3N4B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
Pacchiano, F., Aggarwal, M., Avvaru, B.S., Robbins, A.H., Scozzafava, A., McKenna, R., Supuran, C.T.
Chem.Commun.(Camb.)
HeaderLyase/Lyase Inhibitor
Released2010-05-21
Resolution1.6
CATH Insert Date13 Mar, 2011

PDB Images (3)

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 13 Mar, 2011 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3n4bA00 18 Mar, 2011 3.10.200.10 Assigned

Uniprot Entries (1)

Accession Gene ID Taxon Description
P00918 CAH2_HUMAN Homo sapiens Carbonate dehydratase II