PDB 3msj

PDB Links
Overview

PDB Information

PDB	3MSJ
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Fragment-based discovery and optimization of BACE1 inhibitors. Madden, J., Dod, J.R., Godemann, R., Kraemer, J., Smith, M., Biniszkiewicz, M., Hallett, D.J., Barker, J., Dyekjaer, J.D., Hesterkamp, T. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2010-04-29
Resolution	1.800
CATH Insert Date	15 Aug, 2010

PDB Images (10)

Image of CATH 3msj

3msj

PDB 3msj

Image of CATH 3msjA

3msjA

PDB Chain 3msjA

Image of CATH 3msjB

3msjB

PDB Chain 3msjB

Image of CATH 3msjC

3msjC

PDB Chain 3msjC

Image of CATH 3msjA01

3msjA01

CATH Domain 3msjA01

Image of CATH 3msjA02

3msjA02

CATH Domain 3msjA02

Image of CATH 3msjB01

3msjB01

CATH Domain 3msjB01

Image of CATH 3msjB02

3msjB02

CATH Domain 3msjB02

Image of CATH 3msjC01

3msjC01

CATH Domain 3msjC01

Image of CATH 3msjC02

3msjC02

CATH Domain 3msjC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	16 Aug, 2010	Chopped
B	16 Aug, 2010	Chopped
C	16 Aug, 2010	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3msjA01	14 Oct, 2010	2.40.70.10	Assigned
3msjA02	14 Oct, 2010	2.40.70.10	Assigned
3msjB01	14 Oct, 2010	2.40.70.10	Assigned
3msjB02	14 Oct, 2010	2.40.70.10	Assigned
3msjC01	14 Oct, 2010	2.40.70.10	Assigned
3msjC02	14 Oct, 2010	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1