PDB 3ml8

PDB Links
Overview

PDB Information

PDB	3ML8
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. Cheng, H., Li, C., Bailey, S., Baxi, S.M., Goulet, L., Guo, L., Hoffman, J., Jiang, Y., Johnson, T.O., Johnson, T.W., Knighton, D.R., Li, J., Liu, K.K., Liu, Z., Marx, M.A., Walls, M., Wells, P.A., Yin, M.J., Zhu, J., Zientek, M. ACS Med Chem Lett
Header	Transferase/Transferase Inhibitor
Released	2010-04-16
Resolution	2.700
CATH Insert Date	06 Jun, 2010

PDB Images (7)

Image of CATH 3ml8

3ml8

PDB 3ml8

Image of CATH 3ml8A

3ml8A

PDB Chain 3ml8A

Image of CATH 3ml8A01

3ml8A01

CATH Domain 3ml8A01

Image of CATH 3ml8A02

3ml8A02

CATH Domain 3ml8A02

Image of CATH 3ml8A03

3ml8A03

CATH Domain 3ml8A03

Image of CATH 3ml8A04

3ml8A04

CATH Domain 3ml8A04

Image of CATH 3ml8A05

3ml8A05

CATH Domain 3ml8A05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	06 Jun, 2010	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3ml8A01	31 Jul, 2010	3.10.20.90	Assigned
3ml8A02	31 Jul, 2010	2.60.40.150	Assigned
3ml8A03	31 Jul, 2010	1.25.40.70	Assigned
3ml8A04	31 Jul, 2010	3.30.1010.10	Assigned
3ml8A05	31 Jul, 2010	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform