PDB Information

PDB3MG7
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit.
Blackburn, C., Gigstad, K.M., Hales, P., Garcia, K., Jones, M., Bruzzese, F.J., Barrett, C., Liu, J.X., Soucy, T.A., Sappal, D.S., Bump, N., Olhava, E.J., Fleming, P., Dick, L.R., Tsu, C., Sintchak, M.D., Blank, J.L.
Biochem.J.
HeaderHydrolase
Released2010-04-05
Resolution2.780
CATH Insert Date22 May, 2011

PDB Images (57)

PDB Prints

PDB Chains (28)

Chain ID Date inserted into CATH CATH Status
1 23 May, 2011 Chopped
2 23 May, 2011 Chopped
A 23 May, 2011 Chopped
B 23 May, 2011 Chopped
C 23 May, 2011 Chopped
D 23 May, 2011 Chopped
E 23 May, 2011 Chopped
F 23 May, 2011 Chopped
G 23 May, 2011 Chopped
H 23 May, 2011 Chopped
I 23 May, 2011 Chopped
J 23 May, 2011 Chopped
K 23 May, 2011 Chopped
L 23 May, 2011 Chopped
M 23 May, 2011 Chopped
N 23 May, 2011 Chopped
O 23 May, 2011 Chopped
P 23 May, 2011 Chopped
Q 23 May, 2011 Chopped
R 23 May, 2011 Chopped
S 23 May, 2011 Chopped
T 23 May, 2011 Chopped
U 23 May, 2011 Chopped
V 23 May, 2011 Chopped
W 23 May, 2011 Chopped
X 23 May, 2011 Chopped
Y 23 May, 2011 Chopped
Z 23 May, 2011 Chopped

CATH Domains (28)

Domain ID Date inserted into CATH Superfamily CATH Status
3mg7100 27 May, 2011 3.60.20.10 Assigned
3mg7200 26 May, 2011 3.60.20.10 Assigned
3mg7A00 04 Feb, 2013 3.60.20.10 Assigned
3mg7B00 04 Feb, 2013 3.60.20.10 Assigned
3mg7C00 04 Feb, 2013 3.60.20.10 Assigned
3mg7D00 08 Feb, 2013 3.60.20.10 Assigned
3mg7E00 26 May, 2011 3.60.20.10 Assigned
3mg7F00 27 May, 2011 3.60.20.10 Assigned
3mg7G00 26 May, 2011 3.60.20.10 Assigned
3mg7H00 26 May, 2011 3.60.20.10 Assigned
3mg7I00 26 May, 2011 3.60.20.10 Assigned
3mg7J00 27 May, 2011 3.60.20.10 Assigned
3mg7K00 27 May, 2011 3.60.20.10 Assigned
3mg7L00 27 May, 2011 3.60.20.10 Assigned
3mg7M00 26 May, 2011 3.60.20.10 Assigned
3mg7N00 27 May, 2011 3.60.20.10 Assigned
3mg7O00 04 Feb, 2013 3.60.20.10 Assigned
3mg7P00 04 Feb, 2013 3.60.20.10 Assigned
3mg7Q00 04 Feb, 2013 3.60.20.10 Assigned
3mg7R00 08 Feb, 2013 3.60.20.10 Assigned
3mg7S00 27 May, 2011 3.60.20.10 Assigned
3mg7T00 26 May, 2011 3.60.20.10 Assigned
3mg7U00 27 May, 2011 3.60.20.10 Assigned
3mg7V00 27 May, 2011 3.60.20.10 Assigned
3mg7W00 27 May, 2011 3.60.20.10 Assigned
3mg7X00 27 May, 2011 3.60.20.10 Assigned
3mg7Y00 27 May, 2011 3.60.20.10 Assigned
3mg7Z00 27 May, 2011 3.60.20.10 Assigned

UniProtKB Entries (28)

Accession Gene ID Taxon Description
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1