PDB 3mg7

PDB Links
Overview

PDB Information

PDB	3MG7
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Blackburn, C., Gigstad, K.M., Hales, P., Garcia, K., Jones, M., Bruzzese, F.J., Barrett, C., Liu, J.X., Soucy, T.A., Sappal, D.S., Bump, N., Olhava, E.J., Fleming, P., Dick, L.R., Tsu, C., Sintchak, M.D., Blank, J.L. Biochem.J.
Header	Hydrolase
Released	2010-04-05
Resolution	2.780
CATH Insert Date	22 May, 2011

PDB Images (57)

3mg7

PDB 3mg7

3mg71

PDB Chain 3mg71

3mg72

PDB Chain 3mg72

3mg7A

PDB Chain 3mg7A

3mg7B

PDB Chain 3mg7B

3mg7C

PDB Chain 3mg7C

3mg7D

PDB Chain 3mg7D

3mg7E

PDB Chain 3mg7E

3mg7F

PDB Chain 3mg7F

3mg7G

PDB Chain 3mg7G

3mg7H

PDB Chain 3mg7H

3mg7I

PDB Chain 3mg7I

3mg7J

PDB Chain 3mg7J

3mg7K

PDB Chain 3mg7K

3mg7L

PDB Chain 3mg7L

3mg7M

PDB Chain 3mg7M

3mg7N

PDB Chain 3mg7N

3mg7O

PDB Chain 3mg7O

3mg7P

PDB Chain 3mg7P

3mg7Q

PDB Chain 3mg7Q

3mg7R

PDB Chain 3mg7R

3mg7S

PDB Chain 3mg7S

3mg7T

PDB Chain 3mg7T

3mg7U

PDB Chain 3mg7U

3mg7V

PDB Chain 3mg7V

3mg7W

PDB Chain 3mg7W

3mg7X

PDB Chain 3mg7X

3mg7Y

PDB Chain 3mg7Y

3mg7Z

PDB Chain 3mg7Z

3mg7100

CATH Domain 3mg7100

3mg7200

CATH Domain 3mg7200

3mg7A00

CATH Domain 3mg7A00

3mg7B00

CATH Domain 3mg7B00

3mg7C00

CATH Domain 3mg7C00

3mg7D00

CATH Domain 3mg7D00

3mg7E00

CATH Domain 3mg7E00

3mg7F00

CATH Domain 3mg7F00

3mg7G00

CATH Domain 3mg7G00

3mg7H00

CATH Domain 3mg7H00

3mg7I00

CATH Domain 3mg7I00

3mg7J00

CATH Domain 3mg7J00

3mg7K00

CATH Domain 3mg7K00

3mg7L00

CATH Domain 3mg7L00

3mg7M00

CATH Domain 3mg7M00

3mg7N00

CATH Domain 3mg7N00

3mg7O00

CATH Domain 3mg7O00

3mg7P00

CATH Domain 3mg7P00

3mg7Q00

CATH Domain 3mg7Q00

3mg7R00

CATH Domain 3mg7R00

3mg7S00

CATH Domain 3mg7S00

3mg7T00

CATH Domain 3mg7T00

3mg7U00

CATH Domain 3mg7U00

3mg7V00

CATH Domain 3mg7V00

3mg7W00

CATH Domain 3mg7W00

3mg7X00

CATH Domain 3mg7X00

3mg7Y00

CATH Domain 3mg7Y00

3mg7Z00

CATH Domain 3mg7Z00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
1	23 May, 2011	Chopped
2	23 May, 2011	Chopped
A	23 May, 2011	Chopped
B	23 May, 2011	Chopped
C	23 May, 2011	Chopped
D	23 May, 2011	Chopped
E	23 May, 2011	Chopped
F	23 May, 2011	Chopped
G	23 May, 2011	Chopped
H	23 May, 2011	Chopped
I	23 May, 2011	Chopped
J	23 May, 2011	Chopped
K	23 May, 2011	Chopped
L	23 May, 2011	Chopped
M	23 May, 2011	Chopped
N	23 May, 2011	Chopped
O	23 May, 2011	Chopped
P	23 May, 2011	Chopped
Q	23 May, 2011	Chopped
R	23 May, 2011	Chopped
S	23 May, 2011	Chopped
T	23 May, 2011	Chopped
U	23 May, 2011	Chopped
V	23 May, 2011	Chopped
W	23 May, 2011	Chopped
X	23 May, 2011	Chopped
Y	23 May, 2011	Chopped
Z	23 May, 2011	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3mg7100	27 May, 2011	3.60.20.10	Assigned
3mg7200	26 May, 2011	3.60.20.10	Assigned
3mg7A00	04 Feb, 2013	3.60.20.10	Assigned
3mg7B00	04 Feb, 2013	3.60.20.10	Assigned
3mg7C00	04 Feb, 2013	3.60.20.10	Assigned
3mg7D00	08 Feb, 2013	3.60.20.10	Assigned
3mg7E00	26 May, 2011	3.60.20.10	Assigned
3mg7F00	27 May, 2011	3.60.20.10	Assigned
3mg7G00	26 May, 2011	3.60.20.10	Assigned
3mg7H00	26 May, 2011	3.60.20.10	Assigned
3mg7I00	26 May, 2011	3.60.20.10	Assigned
3mg7J00	27 May, 2011	3.60.20.10	Assigned
3mg7K00	27 May, 2011	3.60.20.10	Assigned
3mg7L00	27 May, 2011	3.60.20.10	Assigned
3mg7M00	26 May, 2011	3.60.20.10	Assigned
3mg7N00	27 May, 2011	3.60.20.10	Assigned
3mg7O00	04 Feb, 2013	3.60.20.10	Assigned
3mg7P00	04 Feb, 2013	3.60.20.10	Assigned
3mg7Q00	04 Feb, 2013	3.60.20.10	Assigned
3mg7R00	08 Feb, 2013	3.60.20.10	Assigned
3mg7S00	27 May, 2011	3.60.20.10	Assigned
3mg7T00	26 May, 2011	3.60.20.10	Assigned
3mg7U00	27 May, 2011	3.60.20.10	Assigned
3mg7V00	27 May, 2011	3.60.20.10	Assigned
3mg7W00	27 May, 2011	3.60.20.10	Assigned
3mg7X00	27 May, 2011	3.60.20.10	Assigned
3mg7Y00	27 May, 2011	3.60.20.10	Assigned
3mg7Z00	27 May, 2011	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5