PDB 3mg4

PDB Links
Overview

PDB Information

PDB	3MG4
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit. Blackburn, C., Gigstad, K.M., Hales, P., Garcia, K., Jones, M., Bruzzese, F.J., Barrett, C., Liu, J.X., Soucy, T.A., Sappal, D.S., Bump, N., Olhava, E.J., Fleming, P., Dick, L.R., Tsu, C., Sintchak, M.D., Blank, J.L. Biochem.J.
Header	Hydrolase
Released	2010-04-05
Resolution	3.110
CATH Insert Date	08 May, 2011

PDB Images (57)

3mg4

PDB 3mg4

3mg41

PDB Chain 3mg41

3mg42

PDB Chain 3mg42

3mg4A

PDB Chain 3mg4A

3mg4B

PDB Chain 3mg4B

3mg4C

PDB Chain 3mg4C

3mg4D

PDB Chain 3mg4D

3mg4E

PDB Chain 3mg4E

3mg4F

PDB Chain 3mg4F

3mg4G

PDB Chain 3mg4G

3mg4H

PDB Chain 3mg4H

3mg4I

PDB Chain 3mg4I

3mg4J

PDB Chain 3mg4J

3mg4K

PDB Chain 3mg4K

3mg4L

PDB Chain 3mg4L

3mg4M

PDB Chain 3mg4M

3mg4N

PDB Chain 3mg4N

3mg4O

PDB Chain 3mg4O

3mg4P

PDB Chain 3mg4P

3mg4Q

PDB Chain 3mg4Q

3mg4R

PDB Chain 3mg4R

3mg4S

PDB Chain 3mg4S

3mg4T

PDB Chain 3mg4T

3mg4U

PDB Chain 3mg4U

3mg4V

PDB Chain 3mg4V

3mg4W

PDB Chain 3mg4W

3mg4X

PDB Chain 3mg4X

3mg4Y

PDB Chain 3mg4Y

3mg4Z

PDB Chain 3mg4Z

3mg4100

CATH Domain 3mg4100

3mg4200

CATH Domain 3mg4200

3mg4A00

CATH Domain 3mg4A00

3mg4B00

CATH Domain 3mg4B00

3mg4C00

CATH Domain 3mg4C00

3mg4D00

CATH Domain 3mg4D00

3mg4E00

CATH Domain 3mg4E00

3mg4F00

CATH Domain 3mg4F00

3mg4G00

CATH Domain 3mg4G00

3mg4H00

CATH Domain 3mg4H00

3mg4I00

CATH Domain 3mg4I00

3mg4J00

CATH Domain 3mg4J00

3mg4K00

CATH Domain 3mg4K00

3mg4L00

CATH Domain 3mg4L00

3mg4M00

CATH Domain 3mg4M00

3mg4N00

CATH Domain 3mg4N00

3mg4O00

CATH Domain 3mg4O00

3mg4P00

CATH Domain 3mg4P00

3mg4Q00

CATH Domain 3mg4Q00

3mg4R00

CATH Domain 3mg4R00

3mg4S00

CATH Domain 3mg4S00

3mg4T00

CATH Domain 3mg4T00

3mg4U00

CATH Domain 3mg4U00

3mg4V00

CATH Domain 3mg4V00

3mg4W00

CATH Domain 3mg4W00

3mg4X00

CATH Domain 3mg4X00

3mg4Y00

CATH Domain 3mg4Y00

3mg4Z00

CATH Domain 3mg4Z00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
1	09 May, 2011	Chopped
2	09 May, 2011	Chopped
A	09 May, 2011	Chopped
B	09 May, 2011	Chopped
C	09 May, 2011	Chopped
D	09 May, 2011	Chopped
E	09 May, 2011	Chopped
F	09 May, 2011	Chopped
G	09 May, 2011	Chopped
H	09 May, 2011	Chopped
I	09 May, 2011	Chopped
J	09 May, 2011	Chopped
K	09 May, 2011	Chopped
L	09 May, 2011	Chopped
M	09 May, 2011	Chopped
N	09 May, 2011	Chopped
O	09 May, 2011	Chopped
P	09 May, 2011	Chopped
Q	09 May, 2011	Chopped
R	09 May, 2011	Chopped
S	09 May, 2011	Chopped
T	09 May, 2011	Chopped
U	09 May, 2011	Chopped
V	09 May, 2011	Chopped
W	09 May, 2011	Chopped
X	09 May, 2011	Chopped
Y	09 May, 2011	Chopped
Z	09 May, 2011	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3mg4100	15 May, 2011	3.60.20.10	Assigned
3mg4200	15 May, 2011	3.60.20.10	Assigned
3mg4A00	04 Feb, 2013	3.60.20.10	Assigned
3mg4B00	04 Feb, 2013	3.60.20.10	Assigned
3mg4C00	04 Feb, 2013	3.60.20.10	Assigned
3mg4D00	08 Feb, 2013	3.60.20.10	Assigned
3mg4E00	15 May, 2011	3.60.20.10	Assigned
3mg4F00	15 May, 2011	3.60.20.10	Assigned
3mg4G00	14 May, 2011	3.60.20.10	Assigned
3mg4H00	14 May, 2011	3.60.20.10	Assigned
3mg4I00	14 May, 2011	3.60.20.10	Assigned
3mg4J00	14 May, 2011	3.60.20.10	Assigned
3mg4K00	14 May, 2011	3.60.20.10	Assigned
3mg4L00	14 May, 2011	3.60.20.10	Assigned
3mg4M00	14 May, 2011	3.60.20.10	Assigned
3mg4N00	14 May, 2011	3.60.20.10	Assigned
3mg4O00	04 Feb, 2013	3.60.20.10	Assigned
3mg4P00	04 Feb, 2013	3.60.20.10	Assigned
3mg4Q00	04 Feb, 2013	3.60.20.10	Assigned
3mg4R00	08 Feb, 2013	3.60.20.10	Assigned
3mg4S00	14 May, 2011	3.60.20.10	Assigned
3mg4T00	14 May, 2011	3.60.20.10	Assigned
3mg4U00	15 May, 2011	3.60.20.10	Assigned
3mg4V00	15 May, 2011	3.60.20.10	Assigned
3mg4W00	15 May, 2011	3.60.20.10	Assigned
3mg4X00	15 May, 2011	3.60.20.10	Assigned
3mg4Y00	15 May, 2011	3.60.20.10	Assigned
3mg4Z00	15 May, 2011	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5