PDB Information

PDB3M5N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus subtype 1a
Primary Citation
Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding.
Romano, K.P., Ali, A., Royer, W.E., Schiffer, C.A.
Proc.Natl.Acad.Sci.USA
HeaderHydrolase/Hydrolase Inhibitor
Released2010-03-12
Resolution1.900
CATH Insert Date23 Jan, 2011

PDB Images (16)

PDB Prints

PDB Chains (7)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
B 24 Jan, 2011 Chopped
C 24 Jan, 2011 Chopped
D 24 Jan, 2011 Chopped
F 24 Jan, 2011 Rejected
G 24 Jan, 2011 Rejected
H 24 Jan, 2011 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3m5nA01 08 Feb, 2013 2.40.10.120 Assigned
3m5nA02 08 Feb, 2013 2.40.10.10 Assigned
3m5nB01 07 Feb, 2013 2.40.10.120 Assigned
3m5nB02 07 Feb, 2013 2.40.10.10 Assigned
3m5nC01 08 Feb, 2013 2.40.10.120 Assigned
3m5nC02 08 Feb, 2013 2.40.10.10 Assigned
3m5nD01 08 Feb, 2013 2.40.10.120 Assigned
3m5nD02 08 Feb, 2013 2.40.10.10 Assigned

UniProtKB Entries (7)

Accession Gene ID Taxon Description
A8DG50 A8DG50_9HEPC Hepatitis C virus subtype 1a Genome polyprotein
B3TKQ3 B3TKQ3_9HEPC Hepatitis C virus subtype 1a Genome polyprotein
A8DG50 A8DG50_9HEPC Hepatitis C virus subtype 1a Genome polyprotein
A8DG50 A8DG50_9HEPC Hepatitis C virus subtype 1a Genome polyprotein
B3TKQ3 B3TKQ3_9HEPC Hepatitis C virus subtype 1a Genome polyprotein
A8DG50 A8DG50_9HEPC Hepatitis C virus subtype 1a Genome polyprotein
B3TKQ3 B3TKQ3_9HEPC Hepatitis C virus subtype 1a Genome polyprotein