PDB Information

PDB3M37
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N-[3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor.
Pruitt, J.R., Pinto, D.J.P., Galemmo, R.A.Jr., Alexander, R.S., Rossi, K.A., Wells, B.L., Drummond, S., Bostrom, L.L., Burdick, D., Bruckner, R., Chen, H., Smallwood, A., Wong, P.C., Wright, M.R., Bai, S., Luettgen, J.M., Knabb, R.M., Lam, P.Y.S., Wexler, R.R.
J.Med.Chem.
HeaderHydrolase
Released2010-03-08
Resolution1.900
CATH Insert Date25 Apr, 2010

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2010 Chopped
L 25 Apr, 2010 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
3m37A01 28 Jul, 2010 2.40.10.10 Assigned
3m37A02 28 Jul, 2010 2.40.10.10 Assigned
3m37L00 28 Jul, 2010 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X