PDB 3lpb

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB Links
Overview

PDB Information

PDB	3LPB
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors Pissot-Soldermann, C., Gerspacher, M., Furet, P., Gaul, C., Holzer, P., McCarthy, C., Radimerski, T., Regnier, C.H., Baffert, F., Drueckes, P., Tavares, G.A., Vangrevelinghe, E., Blasco, F., Ottaviani, G., Ossola, F., Scesa, J., Reetz, J. Bioorg.Med.Chem.Lett.
Header	Transferase
Released	2010-02-05
Resolution	2.000
CATH Insert Date	02 May, 2010

PDB Images (7)

Image of CATH 3lpb

3lpb

PDB 3lpb

Image of CATH 3lpbA

3lpbA

PDB Chain 3lpbA

Image of CATH 3lpbB

3lpbB

PDB Chain 3lpbB

Image of CATH 3lpbA01

3lpbA01

CATH Domain 3lpbA01

Image of CATH 3lpbA02

3lpbA02

CATH Domain 3lpbA02

Image of CATH 3lpbB01

3lpbB01

CATH Domain 3lpbB01

Image of CATH 3lpbB02

3lpbB02

CATH Domain 3lpbB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	03 May, 2010	Chopped
B	03 May, 2010	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3lpbA01	21 Jul, 2010	3.30.200.20	Assigned
3lpbA02	21 Jul, 2010	1.10.510.10	Assigned
3lpbB01	21 Jul, 2010	3.30.200.20	Assigned
3lpbB02	21 Jul, 2010	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2