PDB 3krj

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Overview

PDB Information

PDB	3KRJ
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Optimization of a Potent Class of Arylamide Colony-Stimulating Factor-1 Receptor Inhibitors Leading to Anti-inflammatory Clinical Candidate 4-Cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141). Illig, C.R., Manthey, C.L., Wall, M.J., Meegalla, S.K., Chen, J., Wilson, K.J., Ballentine, S.K., Desjarlais, R.L., Schubert, C., Crysler, C.S., Chen, Y., Molloy, C.J., Chaikin, M.A., Donatelli, R.R., Yurkow, E., Zhou, Z., Player, M.R., Tomczuk, B.E. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2009-11-18
Resolution	2.100
CATH Insert Date	23 Jan, 2011

PDB Images (4)

Image of CATH 3krj

3krj

PDB 3krj

Image of CATH 3krjA

3krjA

PDB Chain 3krjA

Image of CATH 3krjA01

3krjA01

CATH Domain 3krjA01

Image of CATH 3krjA02

3krjA02

CATH Domain 3krjA02

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	24 Jan, 2011	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3krjA01	17 Feb, 2011	3.30.200.20	Assigned
3krjA02	17 Feb, 2011	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P07333	CSF1R_HUMAN	Homo sapiens	Macrophage colony-stimulating factor 1 receptor
P11362	FGFR1_HUMAN	Homo sapiens	Fibroblast growth factor receptor 1