PDB 3km4

PDB Information

PDB3KM4
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Optimization of orally bioavailable alkyl amine renin inhibitors.
Xu, Z., Cacatian, S., Yuan, J., Simpson, R.D., Jia, L., Zhao, W., Tice, C.M., Flaherty, P.T., Guo, J., Ishchenko, A., Singh, S.B., Wu, Z., McKeever, B.M., Scott, B.B., Bukhtiyarov, Y., Berbaum, J., Mason, J., Panemangalore, R., Cappiello, M.G., Bentley, R., Doe, C.P., Harrison, R.K., McGeehan, G.M., Dillard, L.W., Baldwin, J.J., Claremon, D.A.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2009-11-09
Resolution1.900
CATH Insert Date14 Jan, 2010

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Jan, 2010 Chopped
B 15 Jan, 2010 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3km4A01 19 Apr, 2010 2.40.70.10 Assigned
3km4A02 19 Apr, 2010 2.40.70.10 Assigned
3km4B01 19 Apr, 2010 2.40.70.10 Assigned
3km4B02 19 Apr, 2010 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin
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