PDB 3k5g

PDB Links
Overview

PDB Information

PDB	3K5G
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors. Hanessian, S., Shao, Z., Betschart, C., Rondeau, J.M., Neumann, U., Tintelnot-Blomley, M. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2009-10-07
Resolution	2.000
CATH Insert Date	09 May, 2010

PDB Images (10)

Image of CATH 3k5g

3k5g

PDB 3k5g

Image of CATH 3k5gA

3k5gA

PDB Chain 3k5gA

Image of CATH 3k5gB

3k5gB

PDB Chain 3k5gB

Image of CATH 3k5gC

3k5gC

PDB Chain 3k5gC

Image of CATH 3k5gA01

3k5gA01

CATH Domain 3k5gA01

Image of CATH 3k5gA02

3k5gA02

CATH Domain 3k5gA02

Image of CATH 3k5gB01

3k5gB01

CATH Domain 3k5gB01

Image of CATH 3k5gB02

3k5gB02

CATH Domain 3k5gB02

Image of CATH 3k5gC01

3k5gC01

CATH Domain 3k5gC01

Image of CATH 3k5gC02

3k5gC02

CATH Domain 3k5gC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	10 May, 2010	Chopped
B	10 May, 2010	Chopped
C	10 May, 2010	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3k5gA01	13 Jun, 2010	2.40.70.10	Assigned
3k5gA02	13 Jun, 2010	2.40.70.10	Assigned
3k5gB01	13 Jun, 2010	2.40.70.10	Assigned
3k5gB02	13 Jun, 2010	2.40.70.10	Assigned
3k5gC01	13 Jun, 2010	2.40.70.10	Assigned
3k5gC02	13 Jun, 2010	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1