PDB 3k5f

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PDB Links
Overview

PDB Information

PDB	3K5F
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors. Hanessian, S., Shao, Z., Betschart, C., Rondeau, J.M., Neumann, U., Tintelnot-Blomley, M. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2009-10-07
Resolution	2.250
CATH Insert Date	09 May, 2010

PDB Images (10)

Image of CATH 3k5f

3k5f

PDB 3k5f

Image of CATH 3k5fA

3k5fA

PDB Chain 3k5fA

Image of CATH 3k5fB

3k5fB

PDB Chain 3k5fB

Image of CATH 3k5fC

3k5fC

PDB Chain 3k5fC

Image of CATH 3k5fA01

3k5fA01

CATH Domain 3k5fA01

Image of CATH 3k5fA02

3k5fA02

CATH Domain 3k5fA02

Image of CATH 3k5fB01

3k5fB01

CATH Domain 3k5fB01

Image of CATH 3k5fB02

3k5fB02

CATH Domain 3k5fB02

Image of CATH 3k5fC01

3k5fC01

CATH Domain 3k5fC01

Image of CATH 3k5fC02

3k5fC02

CATH Domain 3k5fC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	10 May, 2010	Chopped
B	10 May, 2010	Chopped
C	10 May, 2010	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3k5fA01	13 Jun, 2010	2.40.70.10	Assigned
3k5fA02	13 Jun, 2010	2.40.70.10	Assigned
3k5fB01	13 Jun, 2010	2.40.70.10	Assigned
3k5fB02	13 Jun, 2010	2.40.70.10	Assigned
3k5fC01	13 Jun, 2010	2.40.70.10	Assigned
3k5fC02	13 Jun, 2010	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1