PDB 3k5d

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PDB Links
Overview

PDB Information

PDB	3K5D
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors. Hanessian, S., Shao, Z., Betschart, C., Rondeau, J.M., Neumann, U., Tintelnot-Blomley, M. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2009-10-07
Resolution	2.900
CATH Insert Date	09 May, 2010

PDB Images (10)

Image of CATH 3k5d

3k5d

PDB 3k5d

Image of CATH 3k5dA

3k5dA

PDB Chain 3k5dA

Image of CATH 3k5dB

3k5dB

PDB Chain 3k5dB

Image of CATH 3k5dC

3k5dC

PDB Chain 3k5dC

Image of CATH 3k5dA01

3k5dA01

CATH Domain 3k5dA01

Image of CATH 3k5dA02

3k5dA02

CATH Domain 3k5dA02

Image of CATH 3k5dB01

3k5dB01

CATH Domain 3k5dB01

Image of CATH 3k5dB02

3k5dB02

CATH Domain 3k5dB02

Image of CATH 3k5dC01

3k5dC01

CATH Domain 3k5dC01

Image of CATH 3k5dC02

3k5dC02

CATH Domain 3k5dC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	10 May, 2010	Chopped
B	10 May, 2010	Chopped
C	10 May, 2010	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3k5dA01	13 Jun, 2010	2.40.70.10	Assigned
3k5dA02	13 Jun, 2010	2.40.70.10	Assigned
3k5dB01	13 Jun, 2010	2.40.70.10	Assigned
3k5dB02	13 Jun, 2010	2.40.70.10	Assigned
3k5dC01	13 Jun, 2010	2.40.70.10	Assigned
3k5dC02	13 Jun, 2010	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1