PDB 3ixk

PDB Links
Overview

PDB Information

PDB	3IXK
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central core. Wangsell, F., Gustafsson, K., Kvarnstrom, I., Borkakoti, N., Edlund, M., Jansson, K., Lindberg, J., Hallberg, A., Rosenquist, A., Samuelsson, B. Eur.J.Med.Chem.
Header	Hydrolase
Released	2009-09-04
Resolution	2.500
CATH Insert Date	12 Sep, 2010

PDB Images (10)

Image of CATH 3ixk

3ixk

PDB 3ixk

Image of CATH 3ixkA

3ixkA

PDB Chain 3ixkA

Image of CATH 3ixkB

3ixkB

PDB Chain 3ixkB

Image of CATH 3ixkC

3ixkC

PDB Chain 3ixkC

Image of CATH 3ixkA01

3ixkA01

CATH Domain 3ixkA01

Image of CATH 3ixkA02

3ixkA02

CATH Domain 3ixkA02

Image of CATH 3ixkB01

3ixkB01

CATH Domain 3ixkB01

Image of CATH 3ixkB02

3ixkB02

CATH Domain 3ixkB02

Image of CATH 3ixkC01

3ixkC01

CATH Domain 3ixkC01

Image of CATH 3ixkC02

3ixkC02

CATH Domain 3ixkC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	13 Sep, 2010	Chopped
B	13 Sep, 2010	Chopped
C	13 Sep, 2010	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3ixkA01	19 Sep, 2010	2.40.70.10	Assigned
3ixkA02	19 Sep, 2010	2.40.70.10	Assigned
3ixkB01	19 Sep, 2010	2.40.70.10	Assigned
3ixkB02	19 Sep, 2010	2.40.70.10	Assigned
3ixkC01	19 Sep, 2010	2.40.70.10	Assigned
3ixkC02	19 Sep, 2010	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1