PDB 3irx

PDB Information

PDB3IRX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHuman immunodeficiency virus type 1 BH10
Primary Citation
Crystal Structure of HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor (E)-S-Methyl 5-(1-(3,7-Dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3-methylbenzothioate.
Cullen, M.D., Ho, W.C., Bauman, J.D., Das, K., Arnold, E., Hartman, T.L., Watson, K.M., Buckheit, R.W., Pannecouque, C., De Clercq, E., Cushman, M.
J.Med.Chem.
HeaderTransferase/Hydrolase
Released2009-08-24
Resolution2.800
CATH Insert Date11 Apr, 2010

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2010 Chopped
B 11 Apr, 2010 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
3irxA01 09 May, 2010 3.10.10.10 Assigned
3irxA02 09 May, 2010 3.30.70.270 Assigned
3irxA03 09 May, 2010 3.30.70.270 Assigned
3irxA04 09 May, 2010 3.30.70.270 Assigned
3irxA05 09 May, 2010 3.30.420.10 Assigned
3irxB01 09 May, 2010 3.10.10.10 Assigned
3irxB02 09 May, 2010 3.30.70.270 Assigned
3irxB03 09 May, 2010 3.30.70.270 Assigned
3irxB04 09 May, 2010 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein