PDB 3iro
PDB Information
| PDB | 3IRO |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Trypanosoma cruzi |
| Primary Citation | Structural basis of antifolate inhibition of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate Synthase
To be Published
|
| Header | Oxidoreductase, Transferase |
| Released | 2009-08-24 |
| Resolution | 2.800 |
| CATH Insert Date | 15 Aug, 2010 |
PDB Images (13)
3iro
PDB 3iro
3iroA
PDB Chain 3iroA
3iroB
PDB Chain 3iroB
3iroC
PDB Chain 3iroC
3iroD
PDB Chain 3iroD
3iroA01
CATH Domain 3iroA01
3iroA02
CATH Domain 3iroA02
3iroB01
CATH Domain 3iroB01
3iroB02
CATH Domain 3iroB02
3iroC01
CATH Domain 3iroC01
3iroC02
CATH Domain 3iroC02
3iroD01
CATH Domain 3iroD01
3iroD02
CATH Domain 3iroD02
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Aug, 2010 | Chopped |
| B | 16 Aug, 2010 | Chopped |
| C | 16 Aug, 2010 | Chopped |
| D | 16 Aug, 2010 | Chopped |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3iroA01 | 11 May, 2013 | 3.40.430.10 | Assigned |
| 3iroA02 | 11 May, 2013 | 3.30.572.10 | Assigned |
| 3iroB01 | 11 May, 2013 | 3.40.430.10 | Assigned |
| 3iroB02 | 11 May, 2013 | 3.30.572.10 | Assigned |
| 3iroC01 | 11 May, 2013 | 3.40.430.10 | Assigned |
| 3iroC02 | 11 May, 2013 | 3.30.572.10 | Assigned |
| 3iroD01 | 11 May, 2013 | 3.40.430.10 | Assigned |
| 3iroD02 | 11 May, 2013 | 3.30.572.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q27793 | DRTS_TRYCR | Trypanosoma cruzi | Bifunctional dihydrofolate reductase-thymidylate synthase |
| Q27793 | DRTS_TRYCR | Trypanosoma cruzi | Bifunctional dihydrofolate reductase-thymidylate synthase |
| Q27793 | DRTS_TRYCR | Trypanosoma cruzi | Bifunctional dihydrofolate reductase-thymidylate synthase |
| Q27793 | DRTS_TRYCR | Trypanosoma cruzi | Bifunctional dihydrofolate reductase-thymidylate synthase |
