PDB 3ion

PDB Information

PDB3ION
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-ylamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1).
Nittoli, T., Dushin, R.G., Ingalls, C., Cheung, K., Floyd, M.B., Fraser, H., Olland, A., Hu, Y., Grosu, G., Han, X., Arndt, K., Guo, B., Wissner, A.
Eur.J.Med.Chem.
HeaderTransferase
Released2009-08-14
Resolution2.400
CATH Insert Date11 Feb, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Feb, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3ionA01 02 Apr, 2010 3.30.200.20 Assigned
3ionA02 02 Apr, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O15530 PDPK1_HUMAN Homo sapiens 3-phosphoinositide-dependent protein kinase 1