PDB 3io7

PDB Information

PDB3IO7
MethodX-RAY DIFFRACTION
Host OrganismBaculovirus
Gene SourceHomo sapiens
Primary Citation
2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2.
Ledeboer, M.W., Pierce, A.C., Duffy, J.P., Gao, H., Messersmith, D., Salituro, F.G., Nanthakumar, S., Come, J., Zuccola, H.J., Swenson, L., Shlyakter, D., Mahajan, S., Hoock, T., Fan, B., Tsai, W.J., Kolaczkowski, E., Carrier, S., Hogan, J.K., Zessis, R., Pazhanisamy, S., Bennani, Y.L.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-08-13
Resolution2.600
CATH Insert Date15 Nov, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Nov, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3io7A01 02 Apr, 2010 3.30.200.20 Assigned
3io7A02 02 Apr, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2