PDB 3in4

PDB Information

PDB3IN4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors.
Malamas, M.S., Barnes, K., Johnson, M., Hui, Y., Zhou, P., Turner, J., Hu, Y., Wagner, E., Fan, K., Chopra, R., Olland, A., Bard, J., Pangalos, M., Reinhart, P., Robichaud, A.J.
Bioorg.Med.Chem.
HeaderHydrolase
Released2009-08-11
Resolution2.300
CATH Insert Date21 Jan, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 22 Jan, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3in4A01 01 Apr, 2010 2.40.70.10 Assigned
3in4A02 01 Apr, 2010 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1