PDB 3i25

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

PDB Links
Overview

PDB Information

PDB	3I25
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1' alkoxy residues and an aminoethylene (AE) central core Bjorklund, C., Adolfsson, H., Jansson, K., Lindberg, J., Vrang, L., Hallberg, A., Rosenquist, A., Samuelsson, B. Bioorg.Med.Chem.
Header	Hydrolase
Released	2009-06-29
Resolution	2.100
CATH Insert Date	06 Jun, 2010

PDB Images (10)

Image of CATH 3i25

3i25

PDB 3i25

Image of CATH 3i25A

3i25A

PDB Chain 3i25A

Image of CATH 3i25B

3i25B

PDB Chain 3i25B

Image of CATH 3i25C

3i25C

PDB Chain 3i25C

Image of CATH 3i25A01

3i25A01

CATH Domain 3i25A01

Image of CATH 3i25A02

3i25A02

CATH Domain 3i25A02

Image of CATH 3i25B01

3i25B01

CATH Domain 3i25B01

Image of CATH 3i25B02

3i25B02

CATH Domain 3i25B02

Image of CATH 3i25C01

3i25C01

CATH Domain 3i25C01

Image of CATH 3i25C02

3i25C02

CATH Domain 3i25C02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	06 Jun, 2010	Chopped
B	06 Jun, 2010	Chopped
C	06 Jun, 2010	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3i25A01	10 Jun, 2010	2.40.70.10	Assigned
3i25A02	10 Jun, 2010	2.40.70.10	Assigned
3i25B01	10 Jun, 2010	2.40.70.10	Assigned
3i25B02	10 Jun, 2010	2.40.70.10	Assigned
3i25C01	10 Jun, 2010	2.40.70.10	Assigned
3i25C02	10 Jun, 2010	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1