PDB Information

PDB3HL5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists.
Ndubaku, C., Varfolomeev, E., Wang, L., Zobel, K., Lau, K., Elliott, L.O., Maurer, B., Fedorova, A.V., Dynek, J.N., Koehler, M., Hymowitz, S.G., Tsui, V., Deshayes, K., Fairbrother, W.J., Flygare, J.A., Vucic, D.
Acs Chem.Biol.
HeaderLigase
Released2009-05-26
Resolution1.800
CATH Insert Date16 Aug, 2009

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3hl5A00 04 Feb, 2013 1.10.1170.10 Assigned
3hl5B00 04 Feb, 2013 1.10.1170.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
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