PDB 3hiz

PDB Information

PDB3HIZ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A frequent kinase domain mutation that changes the interaction between PI3K{alpha} and the membrane.
Mandelker, D., Gabelli, S.B., Schmidt-Kittler, O., Zhu, J., Cheong, I., Huang, C.H., Kinzler, K.W., Vogelstein, B., Amzel, L.M.
Proc.Natl.Acad.Sci.USA
HeaderTransferase/Oncoprotein
Released2009-05-20
Resolution3.300
CATH Insert Date01 Oct, 2009

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 01 Oct, 2009 Chopped
B 01 Oct, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3hizA01 04 Sep, 2013 3.10.20.90 Assigned
3hizA02 04 Sep, 2013 1.25.40.70 Assigned
3hizA03 04 Sep, 2013 3.10.20.90 Assigned
3hizA04 04 Sep, 2013 2.60.40.150 Assigned
3hizA05 04 Sep, 2013 3.30.1010.10 Assigned
3hizA06 04 Sep, 2013 1.10.1070.11 Assigned
3hizB01 19 Aug, 2010 3.30.505.10 Assigned
3hizB02 19 Aug, 2010 1.10.287.1490 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27986 P85A_HUMAN Homo sapiens Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336 PK3CA_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform