PDB 3hf9

PDB Links
Overview

PDB Information

PDB	3HF9
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Mycobacterium tuberculosis
Primary Citation	Inhibitors selective for mycobacterial versus human proteasomes. Lin, G., Li, D., de Carvalho, L.P., Deng, H., Tao, H., Vogt, G., Wu, K., Schneider, J., Chidawanyika, T., Warren, J.D., Li, H., Nathan, C. Nature
Header	Hydrolase
Released	2009-05-11
Resolution	2.880
CATH Insert Date	17 Sep, 2009

PDB Images (113)

3hf9

PDB 3hf9

3hf91

PDB Chain 3hf91

3hf92

PDB Chain 3hf92

3hf93

PDB Chain 3hf93

3hf94

PDB Chain 3hf94

3hf9a

PDB Chain 3hf9a

3hf9A

PDB Chain 3hf9A

3hf9b

PDB Chain 3hf9b

3hf9B

PDB Chain 3hf9B

3hf9c

PDB Chain 3hf9c

3hf9C

PDB Chain 3hf9C

3hf9d

PDB Chain 3hf9d

3hf9D

PDB Chain 3hf9D

3hf9e

PDB Chain 3hf9e

3hf9E

PDB Chain 3hf9E

3hf9f

PDB Chain 3hf9f

3hf9F

PDB Chain 3hf9F

3hf9g

PDB Chain 3hf9g

3hf9G

PDB Chain 3hf9G

3hf9h

PDB Chain 3hf9h

3hf9H

PDB Chain 3hf9H

3hf9i

PDB Chain 3hf9i

3hf9I

PDB Chain 3hf9I

3hf9j

PDB Chain 3hf9j

3hf9J

PDB Chain 3hf9J

3hf9k

PDB Chain 3hf9k

3hf9K

PDB Chain 3hf9K

3hf9l

PDB Chain 3hf9l

3hf9L

PDB Chain 3hf9L

3hf9m

PDB Chain 3hf9m

3hf9M

PDB Chain 3hf9M

3hf9n

PDB Chain 3hf9n

3hf9N

PDB Chain 3hf9N

3hf9o

PDB Chain 3hf9o

3hf9O

PDB Chain 3hf9O

3hf9p

PDB Chain 3hf9p

3hf9P

PDB Chain 3hf9P

3hf9q

PDB Chain 3hf9q

3hf9Q

PDB Chain 3hf9Q

3hf9r

PDB Chain 3hf9r

3hf9R

PDB Chain 3hf9R

3hf9s

PDB Chain 3hf9s

3hf9S

PDB Chain 3hf9S

3hf9t

PDB Chain 3hf9t

3hf9T

PDB Chain 3hf9T

3hf9u

PDB Chain 3hf9u

3hf9U

PDB Chain 3hf9U

3hf9v

PDB Chain 3hf9v

3hf9V

PDB Chain 3hf9V

3hf9w

PDB Chain 3hf9w

3hf9W

PDB Chain 3hf9W

3hf9x

PDB Chain 3hf9x

3hf9X

PDB Chain 3hf9X

3hf9y

PDB Chain 3hf9y

3hf9Y

PDB Chain 3hf9Y

3hf9z

PDB Chain 3hf9z

3hf9Z

PDB Chain 3hf9Z

3hf9100

CATH Domain 3hf9100

3hf9200

CATH Domain 3hf9200

3hf9300

CATH Domain 3hf9300

3hf9400

CATH Domain 3hf9400

3hf9a00

CATH Domain 3hf9a00

3hf9A00

CATH Domain 3hf9A00

3hf9b00

CATH Domain 3hf9b00

3hf9B00

CATH Domain 3hf9B00

3hf9c00

CATH Domain 3hf9c00

3hf9C00

CATH Domain 3hf9C00

3hf9d00

CATH Domain 3hf9d00

3hf9D00

CATH Domain 3hf9D00

3hf9e00

CATH Domain 3hf9e00

3hf9E00

CATH Domain 3hf9E00

3hf9f00

CATH Domain 3hf9f00

3hf9F00

CATH Domain 3hf9F00

3hf9g00

CATH Domain 3hf9g00

3hf9G00

CATH Domain 3hf9G00

3hf9h00

CATH Domain 3hf9h00

3hf9H00

CATH Domain 3hf9H00

3hf9i00

CATH Domain 3hf9i00

3hf9I00

CATH Domain 3hf9I00

3hf9j00

CATH Domain 3hf9j00

3hf9J00

CATH Domain 3hf9J00

3hf9k00

CATH Domain 3hf9k00

3hf9K00

CATH Domain 3hf9K00

3hf9l00

CATH Domain 3hf9l00

3hf9L00

CATH Domain 3hf9L00

3hf9m00

CATH Domain 3hf9m00

3hf9M00

CATH Domain 3hf9M00

3hf9n00

CATH Domain 3hf9n00

3hf9N00

CATH Domain 3hf9N00

3hf9o00

CATH Domain 3hf9o00

3hf9O00

CATH Domain 3hf9O00

3hf9p00

CATH Domain 3hf9p00

3hf9P00

CATH Domain 3hf9P00

3hf9q00

CATH Domain 3hf9q00

3hf9Q00

CATH Domain 3hf9Q00

3hf9r00

CATH Domain 3hf9r00

3hf9R00

CATH Domain 3hf9R00

3hf9s00

CATH Domain 3hf9s00

3hf9S00

CATH Domain 3hf9S00

3hf9t00

CATH Domain 3hf9t00

3hf9T00

CATH Domain 3hf9T00

3hf9u00

CATH Domain 3hf9u00

3hf9U00

CATH Domain 3hf9U00

3hf9v00

CATH Domain 3hf9v00

3hf9V00

CATH Domain 3hf9V00

3hf9w00

CATH Domain 3hf9w00

3hf9W00

CATH Domain 3hf9W00

3hf9x00

CATH Domain 3hf9x00

3hf9X00

CATH Domain 3hf9X00

3hf9y00

CATH Domain 3hf9y00

3hf9Y00

CATH Domain 3hf9Y00

3hf9z00

CATH Domain 3hf9z00

3hf9Z00

CATH Domain 3hf9Z00

PDB Prints

PDB Chains (56)

Chain ID	Date inserted into CATH	CATH Status
1	17 Sep, 2009	Chopped
2	17 Sep, 2009	Chopped
3	17 Sep, 2009	Chopped
4	17 Sep, 2009	Chopped
a	17 Sep, 2009	Chopped
A	17 Sep, 2009	Chopped
b	17 Sep, 2009	Chopped
B	17 Sep, 2009	Chopped
c	17 Sep, 2009	Chopped
C	17 Sep, 2009	Chopped
d	17 Sep, 2009	Chopped
D	17 Sep, 2009	Chopped
e	17 Sep, 2009	Chopped
E	17 Sep, 2009	Chopped
f	17 Sep, 2009	Chopped
F	17 Sep, 2009	Chopped
g	17 Sep, 2009	Chopped
G	17 Sep, 2009	Chopped
h	17 Sep, 2009	Chopped
H	17 Sep, 2009	Chopped
i	17 Sep, 2009	Chopped
I	17 Sep, 2009	Chopped
j	17 Sep, 2009	Chopped
J	17 Sep, 2009	Chopped
k	17 Sep, 2009	Chopped
K	17 Sep, 2009	Chopped
l	17 Sep, 2009	Chopped
L	17 Sep, 2009	Chopped
m	17 Sep, 2009	Chopped
M	17 Sep, 2009	Chopped
n	17 Sep, 2009	Chopped
N	17 Sep, 2009	Chopped
o	17 Sep, 2009	Chopped
O	17 Sep, 2009	Chopped
p	17 Sep, 2009	Chopped
P	17 Sep, 2009	Chopped
q	17 Sep, 2009	Chopped
Q	17 Sep, 2009	Chopped
r	17 Sep, 2009	Chopped
R	17 Sep, 2009	Chopped
s	17 Sep, 2009	Chopped
S	17 Sep, 2009	Chopped
t	17 Sep, 2009	Chopped
T	17 Sep, 2009	Chopped
u	17 Sep, 2009	Chopped
U	17 Sep, 2009	Chopped
v	17 Sep, 2009	Chopped
V	17 Sep, 2009	Chopped
w	17 Sep, 2009	Chopped
W	17 Sep, 2009	Chopped
x	17 Sep, 2009	Chopped
X	17 Sep, 2009	Chopped
y	17 Sep, 2009	Chopped
Y	17 Sep, 2009	Chopped
z	17 Sep, 2009	Chopped
Z	17 Sep, 2009	Chopped

CATH Domains (56)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3hf9100	12 Feb, 2010	3.60.20.10	Assigned
3hf9200	16 Mar, 2011	3.60.20.10	Assigned
3hf9300	12 Feb, 2010	3.60.20.10	Assigned
3hf9400	16 Mar, 2011	3.60.20.10	Assigned
3hf9a00	19 Aug, 2010	3.60.20.10	Assigned
3hf9A00	19 Aug, 2010	3.60.20.10	Assigned
3hf9b00	19 Aug, 2010	3.60.20.10	Assigned
3hf9B00	19 Aug, 2010	3.60.20.10	Assigned
3hf9c00	16 Mar, 2011	3.60.20.10	Assigned
3hf9C00	16 Mar, 2011	3.60.20.10	Assigned
3hf9d00	19 Aug, 2010	3.60.20.10	Assigned
3hf9D00	19 Aug, 2010	3.60.20.10	Assigned
3hf9e00	16 Mar, 2011	3.60.20.10	Assigned
3hf9E00	16 Mar, 2011	3.60.20.10	Assigned
3hf9f00	19 Aug, 2010	3.60.20.10	Assigned
3hf9F00	19 Aug, 2010	3.60.20.10	Assigned
3hf9g00	16 Mar, 2011	3.60.20.10	Assigned
3hf9G00	16 Mar, 2011	3.60.20.10	Assigned
3hf9h00	16 Mar, 2011	3.60.20.10	Assigned
3hf9H00	16 Mar, 2011	3.60.20.10	Assigned
3hf9i00	19 Aug, 2010	3.60.20.10	Assigned
3hf9I00	19 Aug, 2010	3.60.20.10	Assigned
3hf9j00	16 Mar, 2011	3.60.20.10	Assigned
3hf9J00	16 Mar, 2011	3.60.20.10	Assigned
3hf9k00	19 Aug, 2010	3.60.20.10	Assigned
3hf9K00	19 Aug, 2010	3.60.20.10	Assigned
3hf9l00	16 Mar, 2011	3.60.20.10	Assigned
3hf9L00	16 Mar, 2011	3.60.20.10	Assigned
3hf9m00	19 Aug, 2010	3.60.20.10	Assigned
3hf9M00	19 Aug, 2010	3.60.20.10	Assigned
3hf9n00	16 Mar, 2011	3.60.20.10	Assigned
3hf9N00	16 Mar, 2011	3.60.20.10	Assigned
3hf9o00	19 Aug, 2010	3.60.20.10	Assigned
3hf9O00	19 Aug, 2010	3.60.20.10	Assigned
3hf9p00	16 Mar, 2011	3.60.20.10	Assigned
3hf9P00	16 Mar, 2011	3.60.20.10	Assigned
3hf9q00	19 Aug, 2010	3.60.20.10	Assigned
3hf9Q00	19 Aug, 2010	3.60.20.10	Assigned
3hf9r00	16 Mar, 2011	3.60.20.10	Assigned
3hf9R00	16 Mar, 2011	3.60.20.10	Assigned
3hf9s00	19 Aug, 2010	3.60.20.10	Assigned
3hf9S00	19 Aug, 2010	3.60.20.10	Assigned
3hf9t00	16 Mar, 2011	3.60.20.10	Assigned
3hf9T00	16 Mar, 2011	3.60.20.10	Assigned
3hf9u00	19 Aug, 2010	3.60.20.10	Assigned
3hf9U00	19 Aug, 2010	3.60.20.10	Assigned
3hf9v00	16 Mar, 2011	3.60.20.10	Assigned
3hf9V00	16 Mar, 2011	3.60.20.10	Assigned
3hf9w00	19 Aug, 2010	3.60.20.10	Assigned
3hf9W00	18 Aug, 2010	3.60.20.10	Assigned
3hf9x00	16 Mar, 2011	3.60.20.10	Assigned
3hf9X00	16 Mar, 2011	3.60.20.10	Assigned
3hf9y00	19 Aug, 2010	3.60.20.10	Assigned
3hf9Y00	19 Aug, 2010	3.60.20.10	Assigned
3hf9z00	16 Mar, 2011	3.60.20.10	Assigned
3hf9Z00	16 Mar, 2011	3.60.20.10	Assigned

UniProtKB Entries (56)

Accession	Gene ID	Taxon	Description
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha
P9WHU1	PSA_MYCTU	Mycobacterium tuberculosis H37Rv	Proteasome subunit alpha