PDB 3hc8

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Overview

PDB Information

PDB	3HC8
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system. Hughes, R.O., Walker, J.K., Cubbage, J.W., Fobian, Y.M., Rogier, D.J., Heasley, S.E., Blevis-Bal, R.M., Benson, A.G., Owen, D.R., Jacobsen, E.J., Freskos, J.N., Molyneaux, J.M., Brown, D.L., Stallings, W.C., Acker, B.A., Maddux, T.M., Tollefson, M.B., Williams, J.M., Moon, J.B., Mischke, B.V., Rumsey, J.M., Zheng, Y., Macinnes, A., Bond, B.R., Yu, Y. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2009-05-05
Resolution	1.790
CATH Insert Date	16 Aug, 2009

PDB Images (3)

Image of CATH 3hc8

3hc8

PDB 3hc8

Image of CATH 3hc8A

3hc8A

PDB Chain 3hc8A

Image of CATH 3hc8A00

3hc8A00

CATH Domain 3hc8A00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	16 Aug, 2009	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3hc8A00	10 Feb, 2010	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27815	PDE4A_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4A
O76074	PDE5A_HUMAN	Homo sapiens	cGMP-specific 3',5'-cyclic phosphodiesterase