PDB Information

PDB3H5B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 (BRU ISOLATE)
Primary Citation
Design of HIV-1 protease inhibitors with pyrrolidinones and oxazolidinones as novel P1'-ligands to enhance backbone-binding interactions with protease: synthesis, biological evaluation, and protein-ligand X-ray studies.
Ghosh, A.K., Leshchenko-Yashchuk, S., Anderson, D.D., Baldridge, A., Noetzel, M., Miller, H.B., Tie, Y., Wang, Y.F., Koh, Y., Weber, I.T., Mitsuya, H.
J.Med.Chem.
HeaderHydrolase
Released2009-04-21
Resolution1.290
CATH Insert Date16 Aug, 2009

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3h5bA00 26 Jan, 2010 2.40.70.10 Assigned
3h5bB00 26 Jan, 2010 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03367 POL_HV1BR Human immunodeficiency virus type 1 (BRU ISOLATE) Gag-Pol polyprotein
P03367 POL_HV1BR Human immunodeficiency virus type 1 (BRU ISOLATE) Gag-Pol polyprotein