PDB 3h10

PDB Links
Overview

PDB Information

PDB	3H10
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B. Aliagas-Martin, I., Burdick, D., Corson, L., Dotson, J., Drummond, J., Fields, C., Huang, O.W., Hunsaker, T., Kleinheinz, T., Krueger, E., Liang, J., Moffat, J., Phillips, G., Pulk, R., Rawson, T.E., Ultsch, M., Walker, L., Wiesmann, C., Zhang, B., Zhu, B.Y., Cochran, A.G. J.Med.Chem.
Header	Transferase
Released	2009-04-10
Resolution	2.200
CATH Insert Date	16 Aug, 2009

PDB Images (10)

Image of CATH 3h10

3h10

PDB 3h10

Image of CATH 3h10A

3h10A

PDB Chain 3h10A

Image of CATH 3h10B

3h10B

PDB Chain 3h10B

Image of CATH 3h10D

3h10D

PDB Chain 3h10D

Image of CATH 3h10A01

3h10A01

CATH Domain 3h10A01

Image of CATH 3h10A02

3h10A02

CATH Domain 3h10A02

Image of CATH 3h10B01

3h10B01

CATH Domain 3h10B01

Image of CATH 3h10B02

3h10B02

CATH Domain 3h10B02

Image of CATH 3h10D01

3h10D01

CATH Domain 3h10D01

Image of CATH 3h10D02

3h10D02

CATH Domain 3h10D02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	16 Aug, 2009	Chopped
B	16 Aug, 2009	Chopped
D	16 Aug, 2009	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3h10A01	23 Jan, 2010	3.30.200.20	Assigned
3h10A02	23 Jan, 2010	1.10.510.10	Assigned
3h10B01	23 Jan, 2010	3.30.200.20	Assigned
3h10B02	23 Jan, 2010	1.10.510.10	Assigned
3h10D01	23 Jan, 2010	3.30.200.20	Assigned
3h10D02	23 Jan, 2010	1.10.510.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A